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  <xsd:element id="zvra_FairValueAdjustmentOfPutOptionNetOfTax" name="FairValueAdjustmentOfPutOptionNetOfTax" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="zvra_FairValueAdjustmentOfWarrantsAndCvrLiability" name="FairValueAdjustmentOfWarrantsAndCvrLiability" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="zvra_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityCumulativeEffectAdjustment" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityCumulativeEffectAdjustment" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
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  <xsd:element abstract="true" id="zvra_statement-statement-note-k-leases-supplement-balance-sheet-information-related-to-lease-details" name="statement-statement-note-k-leases-supplement-balance-sheet-information-related-to-lease-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="zvra_statement-statement-note-k-leases-supplement-cash-flow-information-related-to-leases-details" name="statement-statement-note-k-leases-supplement-cash-flow-information-related-to-leases-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="zvra_statement-statement-note-k-leases-tables" name="statement-statement-note-k-leases-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="zvra_statement-statement-note-l-merger-estimates-and-assumptions-related-to-fair-value-of-assets-and-liabilities-acquired-details" name="statement-statement-note-l-merger-estimates-and-assumptions-related-to-fair-value-of-assets-and-liabilities-acquired-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="zvra_statement-statement-note-l-merger-pro-forma-combined-results-of-operations-details" name="statement-statement-note-l-merger-pro-forma-combined-results-of-operations-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="zvra_statement-statement-note-l-merger-reconciliation-of-contingent-consideration-liabilities-details" name="statement-statement-note-l-merger-reconciliation-of-contingent-consideration-liabilities-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="zvra_statement-statement-note-l-merger-tables" name="statement-statement-note-l-merger-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="zvra_statement-statement-significant-accounting-policies-policies" name="statement-statement-significant-accounting-policies-policies" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
</xsd:schema>
