Document And Entity Information
Note To Financial Statement Details Textual
Significant Accounting Policies
Maturities of investments
Note A - Description of Business, Basis of Presentation and Significant Transactions
Note C - Debt Obligations
Note E - Stock and Warrants
Note F - Stock-based Compensation
Mr Pascoe [Member]
Represents Mr. Pascoe.
Note G - Fair Value of Financial Instruments
Note H - Net Loss Per Share
Note I - Leases
Note A - Description of Business, Basis of Presentation and Significant Transactions - Consideration Paid and Purchase Price Allocation for the Acquisition of Arimoclomol (Details)
Line of credit payable
Note C - Debt Obligations - Aggregate Principal Amount (Details)
zvra_EmployeeStockPurchasePlanMaximumNumberOfIssuableShares
Employee Stock Purchase Plan, Maximum Number of Issuable Shares (in shares)
Maximum number of shares that may be issued under Employee Stock Purchase Plan.
Note C - Debt Obligations - Future Minimum Principal Payments (Details)
Note E - Stock and Warrants - Reserved Authorized Shares of Common Stock for Future Issuance (Details)
Note E - Stock and Warrants - Common Stock Activity (Details)
us-gaap_LiabilitiesCurrent
Total current liabilities
Note F - Stock-based Compensation - Stock-based Compensation Expense (Details)
Schedule of Maturities of Long-Term Debt [Table Text Block]
Note G - Fair Value of Financial Instruments - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)
Note H - Net Loss Per Share - Anti-dilutive Securities (Details)
Note H - Net Loss Per Share - Earnings Per Share (Details)
Other current liabilities
Note I - Leases - Lease Cost (Details)
us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable
Business Combination, Consideration Transferred, Equity Interests Issued and Issuable
Note I - Leases - Supplement Cash Flow Information Related to Leases (Details)
Note I - Leases - Supplement Balance Sheet Information Related to Lease (Details)
us-gaap_BusinessCombinationConsiderationTransferred1
Business Combination, Consideration Transferred
Note I - Leases - Maturities of lease Liabilities (Details)
Notes To Financial Statements
Notes To Financial Statements [Abstract]
us-gaap_BusinessCombinationConsiderationTransferredOther1
Business Combination, Consideration Transferred, Other
Acquired in-process research and development
zvra_EstimatedWeightedAverageCostOfCapital
Estimated Weighted Average Cost of Capital
Represents estimated weighted average cost of capital.
us-gaap_BusinessAcquisitionSharePrice
Business Acquisition, Share Price (in dollars per share)
Arimoclomol Purchase Agreement [Member]
Represents Arimoclomol Purchase Agreement.
US Treasury Securities [Member]
Foreign currency translation adjustment
Proceeds from Employee Stock Purchase Plan
Represents proceeds from employee stock purchase plan.
Assumed reserve liability
Asset Acquisition, Consideration Transferred, Estimated Reserve Liability
Represents estimated reserve liability for asset acquisition consideration transferred.
US Government Agencies Debt Securities [Member]
zvra_ContractWithCustomerClawbackLiability
Contract with Customer, Clawback Liability
Represents clawback liability for contract with customer
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares)
zvra_AssetAcquisitionRecognizedIdentifiableAssetsAcquired
Total purchase price to be allocated
Total allocated purchase price
Amount of assets acquired at the acquisition date.
Property and equipment, inventory and assembled workforce acquired
Property and equipment, inventory and assembled workforce acquired.
IPR&D (2)
Asset Acquisition, Recognized Identifiable Assets, Finite-Lived Intangibles
Represents finite-lived intangible assets acquired.
Other comprehensive loss:
us-gaap_PaymentsToAcquireOtherInvestments
Purchases of investments
us-gaap_PaymentsToAcquireNotesReceivable
Payments to Acquire Notes Receivable
Purchases of secured corporate notes
Accounts payable and accrued expenses
JMP and RBCCM [Member]
Represents JMP Securities LLC ("JMP") and RBC Capital Markets, LLC ("RBCCM").
zvra_EquityDistributionAgreementMaximumAggregateOfferingPrice
Equity Distribution Agreement, Maximum Aggregate Offering Price
The maximum aggregate offering price under the equity distribution agreement.
zvra_EquityDistributionAgreementCommissionFeePercentageOfGrossSales
Equity Distribution Agreement, Commission Fee, Percentage of Gross Sales
The percentage of gross sales for commission fee under the equity distribution agreement.
Proceeds from insurance financing arrangements
Represents proceeds from insurance financing arrangements.
Revolving Credit Facility [Member]
Credit Facility [Axis]
Credit Facility [Domain]
zvra_PaymentsOfPrincipalOnInsuranceFinancingArrangements
Payments of principal on insurance financing arrangements
Represents payments of principal on insurance financing arrangements.
us-gaap_PolicyTextBlockAbstract
Accounting Policies
Cash
Payments to Acquire Productive Assets, Total
us-gaap_NotesIssued1
Issuance of secured promissory note for Proposed Merger (Note K)
us-gaap_StockIssued1
Issuance of common stock for Proposed Merger (Note K)
Indefinite-Lived Intangible Assets [Axis]
Indefinite-Lived Intangible Assets, Major Class Name [Domain]
us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Purchases of property and equipment
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized (in shares)
Supplemental disclosure of noncash investing activities:
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized (in shares)
Liabilities and stockholders' equity
us-gaap_LossContingencyAccrualAtCarryingValue
Loss Contingency Accrual
Weighted average number of shares of common stock outstanding:
Operating lease liabilities
us-gaap_Assets
Total assets
Supplemental cash flow information:
Plan Name [Axis]
Plan Name [Domain]
In Process Research and Development [Member]
us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic
Net loss
us-gaap_SubleaseIncome
Less: sublease income
Mergers, Acquisitions and Dispositions Disclosures [Text Block]
Finite-Lived Intangible Assets by Major Class [Axis]
us-gaap_IncomeTaxReceivable
Income Taxes Receivable
Share-Based Payment Arrangement [Text Block]
Finite-Lived Intangible Assets, Major Class Name [Domain]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
us-gaap_ContractWithCustomerAssetNet
Contract with Customer, Asset, after Allowance for Credit Loss, Total
ATM Agreement Sales [Member]
Represents for At-the-Market Agreement Sales.
Business Description and Basis of Presentation [Text Block]
Award Type [Domain]
Award Type [Axis]
Net Income (loss)
Net loss
Net loss
Restricted Stock Units (RSUs) [Member]
Performance Shares [Member]
Share-Based Payment Arrangement [Member]
Warrant [Member]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Antidilutive Securities [Axis]
Antidilutive Securities, Name [Domain]
Commitments and Contingencies Disclosure [Text Block]
us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
less: accumulated depreciation and amortization
Property and equipment, net
Warrant Issued to KVK [Member]
Represents the warrant issued to KVK in connection with a Collaboration and License Agreement.
us-gaap_Investments
Investments
zvra_IncreaseDecreaseInOtherLongtermInvestments
Long-term investments - other
Amount of increase (decrease) in other long-term investments.
Cash flows from investing activities:
zvra_FinancingReceivableMaximumLimit
Financing Receivable, Maximum Limit
The maximum limit of the financing receivable.
Acer Therapeutics Inc [Member]
Represents Acer Therapeutics Inc.
Bridge Loan [Member]
Short-term investments - other
Long-term investments - other
Earnings Per Share [Text Block]
Arimoclomol EAP [Member]
Related to Arimoclomol EAP.
us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Accounts payable and accrued expenses
us-gaap_IncomeTaxExpenseBenefit
Income tax (expense) benefit
President and Chief Executive Officer [Member]
Represents the President and Chief Executive Officer.
Consolidation, Variable Interest Entity, Policy [Policy Text Block]
SWK Loans [Member]
Represents the SWK Loans.
zvra_AnnualPerformancebasedTargetBonusPercentageOfBaseSalary
Annual Performance-based Target Bonus, Percentage of Base Salary
Percentage of base salary for annual performance-based target bonus.
zvra_BaseSalary
Base Salary
Amount of base salary.
zvra_DebtInstrumentInterestRateStatedPercentageIfUnpaidWithinSixMonths
Debt Instrument, Interest Rate, Stated Percentage, If Unpaid Within Six Months
Contractual interest rate for funds borrowed, under the debt agreement, if unpaid within six months.
Nantahala Note [Member]
Represents the Nantahala Note.
zvra_SeveranceCostsRecognized
Severance Costs Recognized
The amount of severance costs recognized.
zvra_DebtInstrumentInterestSharesConsecutiveTradingDaysForCalculationOfVWAP
Debt Instrument, Interest, Shares, Consecutive Trading Days For Calculation of VWAP (Day)
The consecutive trading days for calculation of VWAP for interest to be paid in shares on debt instrument.
zvra_DebtInstrumentInterestRateIncreaseInStatedPercentageIfUnpaidWithinSixMonths
Debt Instrument, Interest Rate, Increase in Stated Percentage, If Unpaid Within Six Months
Increase in the contractual interest rate for funds borrowed, under the debt agreement, if unpaid within six months.
zvra_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuableConversionRatio
Business Combination, Consideration Transferred, Equity Interests Issued and Issuable, Conversion Ratio
Conversion ratio of equity interests of the acquirer, including instruments or interests issued or issuable in consideration for the business combination.
zvra_EmploymentAgreementPeriodOfPostterminationNoncompeteAndNonsolicitations
Employment Agreement, Period of Post-termination Non-compete and Non-solicitations (Month)
Period of post-termination non-compete and non-solicitations in the employment agreement.
zvra_FinancingReceivableInterestRateStatedPercentage
Financing Receivable, Interest Rate, Stated Percentage
Contractual interest rate of financing receivable.
zvra_VwapConsecutiveTradingDays
VWAP, Consecutive Trading Days (Day)
The consecutive trading days for VWAP.
zvra_EmploymentAgreementTerminationWithoutCauseContinuedCobraCoveragePeriod
Employment Agreement, Termination Without Cause, Continued COBRA Coverage Period (Month)
Period of continued COBRA coverage if terminated without cause under employment agreement.
Debt Instrument, Redemption, Period One [Member]
zvra_EmploymentAgreementTerminationWithoutCauseRateOfBaseSalary
Employment Agreement, Termination Without Cause, Rate of Base Salary
The rate of base salary if terminated without cause under the employment agreement.
Debt Instrument, Redemption, Period Two [Member]
Aquestive Therapeutics [Member]
Represents Aquestive Therapeutics (formerly known as MonoSol Rx, LLC).
zvra_EmploymentAgreementTerminationOnChangeOfControlContinuedCobraCoveragePeriod
Employment Agreement, Termination on Change of Control, Continued COBRA Coverage Period (Month)
The period of continued COBRA coverage if terminated on change of control in employment agreement.
zvra_EmploymentAgreementTerminationOnChangeOfControlRateOfBaseSalary
Employment Agreement, Termination on Change of Control, Rate of Base Salary
The rate of base salary to be paid upon termination on change of control in employment agreement.
zvra_ConsultingAgreementConditionalMilestoneAchievementToBeReceived
Consulting Agreement, Conditional Milestone Achievement to be Received
The amount to be received upon conditional milestone achievement under the consulting agreement.
Debt Instrument, Redemption, Period [Axis]
Debt Instrument, Redemption, Period [Domain]
zvra_AssetAcquisitionSharePrice
Asset Acquisition, Share Price (in dollars per share)
The share price of equity interest issued in asset acquisition.
Wells Fargo Bank, N.A. [Member]
Represents the "Wells Fargo Bank, N.A."
zvra_FinancingReceivableIncreaseInMaximumLimit
Financing Receivable, Increase in Maximum Limit
Amount of increase in maximum limit of financing receivable.
Corium, Inc [Member]
Represents Corium, Inc.
zvra_ConsultingAgreementMaximumAmountToBeReceived
Consulting Agreement, Maximum Amount to be Received
The maximum amount to be received under the consulting agreement.
zvra_DebtInstrumentDefaultIncreaseInInterest
Debt Instrument, Default, Increase in Interest
Percentage of increase in interest rate in the event of default on the debt instrument.
zvra_DebtInstrumentSofrFloor
debt Instrument, SOFR Floor
Percentage of SOFR floor on debt instrument.
License Agreement and Termination Agreement [Member]
Represents License Agreement and Termination Agreement.
Marathon Convertible Notes [Member]
Represents the Marathon Convertible Notes.
zvra_LoansReceivableExitFeeRateOfPrincipal
Loans Receivable, Exit Fee, Rate of Principal
Rate of principal for exit fee on loans receivable.
zvra_DebtInstrumentDefaultMaximumInterestRate
Debt Instrument, Default, Maximum Interest Rate
Maximum interest rate in the event of default on the debt instrument.
zvra_DebtInstrumentRedemptionPeriodStart
Debt Instrument, Redemption Period Start (Month)
The start of the redemption period of the debt instrument.
zvra_MaximumRoyaltyObligation
Maximum Royalty Obligation
Amount of maximum royalty obligation.
Worldwide, Excluding Europe [Member]
Represents worldwide, excluding Europe.
SWK Loans and Marathon Notes [Member]
Represents the SWK Loans and Marathon Notes.
Cash and cash equivalents
Relief [Member]
Represents Relief.
zvra_MaximumRoyaltyPercentage
Maximum Royalty Percentage
Percentage of maximum royalty.
zvra_AddiitonalPaymentOnFirstAnniversary
Addiitonal Payment on First Anniversary
Amount of additional payment on first anniversary.
us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities
Other liabilities
zvra_UpfrontPayment
Upfront Payment
Amount of upfront payment.
us-gaap_DebtInstrumentConvertibleConversionPrice1
Debt Instrument, Convertible, Conversion Price (in dollars per share)
Stock based compensation expense
Share-Based Payment Arrangement, Expense
us-gaap_CertificatesOfDepositAtCarryingValue
Certificates of Deposit, at Carrying Value
us-gaap_DebtInstrumentConvertibleNumberOfEquityInstruments
Debt Instrument, Convertible, Number of Equity Instruments
zvra_LineOfCreditFacilityMaximumBorrowingCapacityPercentageOfInvestments
Line of Credit Facility, Maximum Borrowing Capacity, Percentage of Investments
Percentage of investments outstanding for maximum borrowing capacity of the debt instrument.
Amendment Flag
us-gaap_ComprehensiveIncomeNetOfTax
Comprehensive loss
City Area Code
Use of Estimates, Policy [Policy Text Block]
us-gaap_DebtInstrumentPeriodicPaymentInterest
Debt Instrument, Periodic Payment, Interest
us-gaap_TreasuryStockSharesAcquired
Common stock repurchased as a result of the Stock Repurchase Plan (in shares)
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding (in shares)
Balance (in shares)
Balance (in shares)
Preferred stock, shares outstanding (in shares)
Possible Future Issuances Under Employee Stock Purchase Plans [Member]
Represents possible future issuances under employee stock purchase plans.
Current Fiscal Year End Date
us-gaap_DebtInstrumentBasisSpreadOnVariableRate1
Debt Instrument, Basis Spread on Variable Rate
us-gaap_DebtInstrumentInterestRateStatedPercentage
Debt Instrument, Interest Rate, Stated Percentage
us-gaap_NotesReceivableNet
Financing Receivable, after Allowance for Credit Loss
Variable lease cost
us-gaap_LeaseCost
Total lease costs
us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Prepaid expenses and other assets
Operating leases
Document Fiscal Period Focus
Operating lease cost
Document Fiscal Year Focus
Short-term lease cost
Lease, Cost [Table Text Block]
us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability
Finance leases
Document Period End Date
us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
Operating leases
Operating leases (Year)
Entity File Number
Entity Emerging Growth Company
us-gaap_DebtInstrumentFaceAmount
Debt Instrument, Face Amount
Document Type
Entity Small Business
Entity Shell Company
Document Information [Line Items]
Document Information [Table]
Severance expense
Severance Costs
Entity Filer Category
Debt Instrument [Axis]
Entity Current Reporting Status
Debt Instrument, Name [Domain]
us-gaap_RestructuringCharges
Restructuring Charges
us-gaap_BusinessCombinationAcquisitionRelatedCosts
Business Combination, Acquisition Related Costs
Variable Rate [Domain]
Prime Rate [Member]
Schedule of Long-Term Debt Instruments [Table Text Block]
Variable Rate [Axis]
Stock-based compensation expense
SWK Loans and the Marathon Convertible Notes [Member]
Related to SWK Loans and the Marathon Convertible Notes.
us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables
Accounts and other receivables
Statement of Comprehensive Income [Abstract]
Entity Tax Identification Number
Entity Central Index Key
Entity Registrant Name
Entity [Domain]
Legal Entity [Axis]
Entity Address, Address Line One
Entity Address, City or Town
Entity Address, Postal Zip Code
us-gaap_TreasuryStockCommonValue
Treasury Stock, Common, Value
Entity Address, State or Province
us-gaap_AllowanceForDoubtfulAccountsReceivable
Accounts Receivable, Allowance for Credit Loss, Ending Balance
us-gaap_TreasuryStockValue
Treasury stock, at cost
Entity Common Stock, Shares Outstanding
zvra_SaleOfStockAuthorizedAmount
Sale of Stock, Authorized Amount
Amount of stock authorized for sale.
Deerfield Warrant [Member]
Represents the Deerfield Warrant.
us-gaap_IncreaseDecreaseInInventories
Inventories
Trading Symbol
Common stock issued in connection with the Proposed Merger (Note K) (in shares)
Stock Issued During Period, Shares, Acquisitions (in shares)
Common stock issued as a result of the Employee Stock Purchase Plan (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans (in shares)
Local Phone Number
Issuance of common stock in connection with the Proposed Merger (Note K)
us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity
Line of Credit Facility, Remaining Borrowing Capacity
Common stock issued as a result of stock warrants exercised (in shares)
us-gaap_TableTextBlock
Notes Tables
Issuance of common stock as part of the Employee Stock Purchase Plan
us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity
Line of Credit Facility, Maximum Borrowing Capacity
us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures, Total (in shares)
Selling, general and administrative
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares)
Line of Credit Facility, Lender [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
us-gaap_StockIssuedDuringPeriodSharesNewIssues
Stock Issued During Period, Shares, New Issues (in shares)
Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member]
Issuance of common stock in exchange for consulting services
Common stock issued as compensation to third-parties (in shares)
Common stock issued as compensation to third parties (in shares)
Lender Name [Axis]
us-gaap_LiabilitiesAndStockholdersEquity
Total liabilities and stockholders' equity
us-gaap_StockIssuedDuringPeriodValueNewIssues
Stock Issued During Period, Value, New Issues
Asset Pledged as Collateral [Member]
Accumulated deficit
Accumulated other comprehensive (loss) income
Research and development
Debt Disclosure [Text Block]
us-gaap_InterestExpense
Interest expense
Change in assets and liabilities:
Schedule of Authorized Shares of Common Stock Reserved for Future Issuance [Table Text Block]
Tabular disclosure of authorized shares of common stock reserved for future issuance.
us-gaap_DisclosureTextBlockAbstract
Notes to Financial Statements
Subsequent Event [Member]
Operating lease liabilities, less current portion
Possible Future Issuances Under Equity Incentive Plans [Member]
Represents possible future issuances under equity incentive plans.
Total operating lease liabilities
Lease liabilities, operating leases
Subsequent Event Type [Axis]
Current portion of operating lease liabilities
Subsequent Event Type [Domain]
us-gaap_FinanceLeaseLiabilityCurrent
Other current liabilities
us-gaap_FinanceLeaseLiabilityNoncurrent
Other long-term liabilities
Subsequent Events [Text Block]
Operating lease right-of-use assets
Total operating lease right-of-use assets
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue
Total lease payments, operating leases
zvra_SharebasedCompensationArrangementBySharebasedPaymentAwardNumberOfSharesReservedForIssuanceIncrementalPercentageOfCapitalStockOutstanding
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Reserved for Issuance, Incremental Percentage of Capital Stock Outstanding
Represents the share based compensation arrangement by share based payment award number of shares reserved for issuance incremental percentage of capital stock outstanding.
Financing cash flows from finance leases
Repayment of principal on finance lease liabilities
us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
Less: future interest expense, operating leases
us-gaap_FinanceLeaseLiability
Lease liabilities, finance leases
2014 Equity Incentive Plan [Member]
Represents the two thousand fourteen equity incentive plan.
zvra_IncreaseInCommonStockReservedForIssuance
Increase in Common Stock Reserved for Issuance (in shares)
Amount of increase in common stock reserved for issuance.
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree
2026, operating leases
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour
2027, operating leases
us-gaap_UnrealizedGainLossOnInvestments
Unrealized Gain (Loss) on Investments
us-gaap_FinanceLeaseRightOfUseAsset
Property and equipment, net
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
2024, operating leases
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
2025, operating leases
Fair value adjustment related to derivative and warrant liability
Fair value adjustment related to derivative and warrant liability
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Warrants to Purchase Common Stock [Member]
Represents warrants to purchase common stock.
Other long-term assets
us-gaap_ShareBasedCompensation
Stock-based compensation expense
us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear
2023, operating leases
Operating expenses:
zvra_RoyaltyRevenuePercent
Royalty Revenue, Percent
Represents the royalty revenue expressed as a percentage.
Total assets
zvra_RevenueRecognitionMilestoneMethodAdditionalRevenueToBeRecognized
Revenue Recognition, Milestone Method, Additional Revenue to be Recognized
The amount of additional consideration to be recognized for the milestone or milestones.
Consulting Services [Member]
Information pertaining to consulting services.
Depreciation and amortization expense
Inventories
us-gaap_AssetsCurrent
Total current assets
zvra_FinanceLeaseCostTotal
Total finance lease cost
Represents total cost of fiance lease.
us-gaap_InvestmentsFairValueDisclosure
Investments, Fair Value Disclosure
Equity [Text Block]
zvra_LesseeLeaseRemainingTermOfContract
Lessee, Lease, Remaining Term of Contract (Year)
Remaining term of lessee's lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.
Lease Disclosure [Text Block]
The entire disclosure for operating, finance, sale leaseback leases.
us-gaap_TreasuryStockCommonShares
Treasury Stock, Common, Shares (in shares)
Share Repurchase Program [Member]
Common stock, $0.0001 par value, 250,000,000 shares authorized, 37,787,402 shares issued and 36,211,710 shares outstanding as of September 30, 2023; 35,450,257 shares issued and 34,540,304 shares outstanding as of December 31, 2022
Adjustments to reconcile net loss to net cash used in operating activities:
Measurement Frequency [Axis]
Measurement Frequency [Domain]
Fair Value, Recurring [Member]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized (in shares)
Common stock, shares issued (in shares)
Common Stock, Shares, Issued (in shares)
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share (in dollars per share)
Schedule of Leases Cash Flow Information [Table Text Block]
Tabular disclosure of leases related to cash flow information.
Revenue from Contract with Customer [Policy Text Block]
zvra_FinanceLeaseRightofuseAssetGross
Property and equipment, at cost
Gross amount of lessee's right to use underlying asset under finance lease.
Schedule of Leases Balance Sheet Information [Table Text Block]
Tabular disclosure of leases related to balance sheet.
Common shares reserved for future issuance (in shares)
Statistical Measurement [Domain]
Operating cash flows from operating leases
Accumulated Depreciation and Amortization [Member]
Primary financial statement caption encompassing accumulated depreciation and amortization.
Maximum [Member]
Property and Equipment, At Cost [Member]
Primary financial statement caption encompassing property and plant at cost.
Minimum [Member]
Current Portion of Operating Lease Liabilities [Member]
Primary financial statement caption encompassing current portion of operating lease liabilities.
Product and Service [Axis]
Operating cash flows from short-term leases
Operating Lease Right-of-Use Assets [Member]
Primary financial statement caption encompassing operating lease right-of-use assets.
Product and Service [Domain]
Operating cash flows from variable lease costs
Statistical Measurement [Axis]
Operating cash flows from finance leases
Property and Equipment, Net [Member]
Primary financial statement caption encompassing property and equipment, net.
Operating and Finance Lease, Liability, Maturity [Table Text Block]
Tabular disclosure of undiscounted cash flows of operating and finance lease liability. Includes, but is not limited to, reconciliation of undiscounted cash flows to operating and finance lease liability recognized in statement of financial position.
Undesignated preferred stock, $0.0001 par value, 10,000,000 shares authorized, no shares issued or outstanding as of September 30, 2023 or December 31, 2022
Operating Lease Liabilities, Less Current Portion [Member]
Primary financial statement caption encompassing operating lease liabilities, less current portion.
Preferred stock, shares issued (in shares)
Cash paid for interest
Geographical [Axis]
Geographical [Domain]
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized (in shares)
Europe [Member]
zvra_LesseeLeaseOptionToTerminateTerm
Lessee, Lease, Option to Terminate, Term (Year)
Represents the terms of option to terminate lessee's lease.
zvra_LesseeLeaseOptionToExtendMaximumTerm
Lessee, Lease, Option to Extend, Maximum Term (Year)
Represents maximum terms of option to extend lessee's lease.
Preferred stock, par value (in dollars per share)
Revenue, net
Revenue from Contract with Customer, Including Assessed Tax
Fair Value, Inputs, Level 3 [Member]
us-gaap_ForeignCurrencyTransactionGainLossBeforeTax
Gain on foreign currency exchange
Fair Value Hierarchy and NAV [Domain]
Fair Value, Inputs, Level 1 [Member]
Fair Value, Inputs, Level 2 [Member]
Fair Value Hierarchy and NAV [Axis]
us-gaap_InterestIncomeExpenseNet
Interest Income (Expense), Net
Cash flows from operating activities:
Accounts and other receivables
Secured corporate notes
Statement [Line Items]
us-gaap_AccountsReceivableNetCurrent
Accounts Receivable, after Allowance for Credit Loss, Current
Additional paid-in capital
AOCI Attributable to Parent [Member]
Stockholders’ equity:
Securities at fair value
us-gaap_NonoperatingIncomeExpense
Total other income (expense)
Chief Executive Officer [Member]
Other income (expense):
Fair Value Disclosures [Text Block]
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
Cash and cash equivalents, beginning of period
Cash and cash equivalents, end of period
zvra_ApicAdjustmentForSeveranceExpense
Severance expense
Amount of adjustment to additional paid-in-capital for severance expense.
Assets
License [Member]
Effect of exchange rate changes on cash and cash equivalents
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
Net decrease in cash and cash equivalents
us-gaap_Liabilities
Liabilities
Total liabilities
us-gaap_NetCashProvidedByUsedInFinancingActivities
Net cash provided by financing activities
Commitments and contingencies (Note D)
Sale of Stock [Axis]
Sale of Stock [Domain]
us-gaap_OperatingIncomeLoss
Loss from operations
us-gaap_ContractWithCustomerLiabilityRevenueRecognized
Contract with Customer, Liability, Revenue Recognized
us-gaap_NetCashProvidedByUsedInOperatingActivities
Net cash used in operating activities
Prepaid expenses and other current assets
us-gaap_NetCashProvidedByUsedInInvestingActivities
Net cash used in investing activities
Investment, Issuer Name [Domain]
Cost of revenue
Investment, Issuer Name [Axis]
Counterparty Name [Axis]
Counterparty Name [Domain]
Investment, Policy [Policy Text Block]
us-gaap_PaymentsOfStockIssuanceCosts
Payment of offering costs
us-gaap_CostsAndExpenses
Total operating expenses
us-gaap_PaymentsForRepurchaseOfCommonStock
Payments to repurchase shares as part of the Share Repurchase Program
GPC Member
Information regarding the GPC License Agreement.
Retained Earnings [Member]
Undesignated Preferred Stock [Member]
Preferred stock that has been classified as undesignated.
Title of Individual [Domain]
Title of Individual [Axis]
Treasury Stock, Common [Member]
Additional Paid-in Capital [Member]
Share Repurchase Program [Domain]
Common Stock [Member]
us-gaap_StockRepurchaseProgramAuthorizedAmount1
Stock Repurchase Program, Authorized Amount
Equity Components [Axis]
Share Repurchase Program [Axis]
Equity Component [Domain]
Class of Warrant or Right [Axis]
Other Current Liabilities [Member]
Class of Warrant or Right [Domain]
Other Noncurrent Liabilities [Member]
Secured promissory note, net
us-gaap_NotesPayable
Secured promissory note, net
us-gaap_ClassOfWarrantOrRightOutstanding
Class of Warrant or Right, Outstanding (in shares)
us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
Loss before income taxes
us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)
us-gaap_LineOfCredit
Long-Term Line of Credit
us-gaap_LineOfCreditFacilityMaximumAmountOutstandingDuringPeriod
Line of Credit Facility, Maximum Amount Outstanding During Period
us-gaap_DeferredFinanceCostsNet
Less: debt issuance costs
Plus: unamortized debt premium and debt issuance costs
us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
us-gaap_DeferredRevenue
Deferred Revenue, Total
us-gaap_DebtInstrumentUnamortizedDiscountPremiumNet
Unamortized original issue premium
Balance Sheet Location [Axis]
Balance Sheet Location [Domain]
Document Quarterly Report
Receivable [Policy Text Block]
Entity Incorporation, State or Country Code
Secured promissory note
us-gaap_DebtInstrumentCarryingAmount
Total minimum payments
General and Administrative Expense [Member]
Accounting Policies [Abstract]
Significant Accounting Policies [Text Block]
Document Transition Report
Entity Interactive Data Current
Security Exchange Name
Title of 12(b) Security
us-gaap_ProceedsFromIssuanceOfLongTermDebt
Proceeds from Issuance of Long-Term Debt
Receivable Type [Axis]
Receivable [Domain]
Research and Development Expense [Member]
Income Statement Location [Axis]
Income Statement Location [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
us-gaap_ContractualObligation
Contractual Obligation
Antidilutive securities (in shares)
us-gaap_RepaymentsOfLinesOfCredit
Repayments of Lines of Credit
Asset Class [Axis]
Asset Class [Domain]
Statement [Table]
Statement of Financial Position [Abstract]
Basic and diluted (in shares)
Weighted average number of shares of common stock outstanding, basic and diluted (in shares)
Business Acquisition [Axis]
Basic and diluted net loss per share of common stock (in dollars per share)
Net loss (in dollars per share)
Business Acquisition, Acquiree [Domain]
Basic and diluted net loss per share of common stock:
Statement of Cash Flows [Abstract]
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear
2023
us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High
Statement of Stockholders' Equity [Abstract]
Income Statement [Abstract]
Other comprehensive loss
Other comprehensive loss:
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree
2026
The 2023 Plan [Member]
Represents the 2023 Employment Inducement Award Plan.
us-gaap_RestructuringReserve
Restructuring Reserve
us-gaap_BusinessCombinationContingentConsiderationLiability
Business Combination, Contingent Consideration, Liability
Proceeds from issuance of debt
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths
2024
us-gaap_RepaymentsOfDebt
Repayment of debt
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo
2025
zvra_TransitionAgreementContinuedPaymentOfBaseSalaryPeriod
Transition Agreement, Continued Payment of Base Salary, Period (Month)
Period of continued payment of base salary under transition agreement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.
zvra_TransitionAgreementContinuedMedicalDentalAndVisionCoveragePeriod
Transition Agreement, Continued Medical, Dental and Vision Coverage, Period (Month)
Period of continued medical, dental and vision coverage under transition agreement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.
zvra_TransitionAgreementMonthlyConsultingFees
Transition Agreement, Monthly Consulting Fees
Amount of monthly consulting fees under the transition agreement.
Significant Events [Text Block]
The entire disclosure for significant events.
Interest on lease liabilities
us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares (in shares)
zvra_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingNumberOfInstallments
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Number of Installments
The number of installments over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition.
Company's President and Former Chief Executive Officer [Member]
Represents the Company’s President and former Chief Executive Officer.
Loss on sublease and disposal of property and equipment
Represents the loss on sublease and disposal of property and equipment recognized during the period.
us-gaap_FinanceLeaseLiabilityPaymentsDue
Total lease payments, finance leases
Amortization of right-of-use assets
Ameris Bank [Member]
Represents Ameris Bank.
us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount
Less: future interest expense, finance leases
us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths
2024, finance leases
us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo
2025, finance leases
us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree
2026, finance leases
us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour
2027, finance leases
Asset Acquisition [Axis]
Total consideration
Total consideration
Type of Restructuring [Domain]
Interest and other income, net
Represents the amount of interest and other income (expense), net, recognized during the period.
Finance leases
Employee Severance [Member]
us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear
2023, finance leases
Direct transaction costs associated with the acquisition (1)
Restructuring Type [Axis]
Finance leases (Year)
Cash flows from financing activities:
us-gaap_AssetAcquisitionConsiderationTransferredEquityInterestIssuedAndIssuable
Asset Acquisition, Consideration Transferred, Equity Interest Issued and Issuable
Schedule of Common Stock Outstanding Roll Forward [Table Text Block]
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Other long-term liabilities
Asset Acquisition [Domain]
Consulting fees paid in common stock
The amount of consulting fees are paid in stock.
Asset Acquisition [Table Text Block]
Fair value adjustment related to investments
Fair value adjustment related to investments
Amount of expense (income) related to adjustment to fair value of investments.
zvra_ClassOfWarrantOrRightExercisableDuringPeriod
Class of Warrant or Right, Exercisable During Period (in shares)
Represents the number of warrants that are exercisable during the period.
zvra_IncreaseDecreaseInOperatingLeaseRightofuseAsset
Operating lease right-of-use assets
The amount of increase (decrease) in operating lease right-of-use assets.
Pledged Status [Domain]
Pledged Status [Axis]
Current portion of discount and rebate liabilities
Current portion of discount and rebate liabilities.
Discount and rebate liabilities, less current portion
Noncurrent portion of discount and rebate liabilities.
us-gaap_StockholdersEquity
Total stockholders' equity
Balance
Balance
us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired
Acquisitions, net
Class of Stock [Axis]
Class of Stock [Domain]
zvra_TreasuryStockValueAcquired
Shares repurchased as part of the Share Repurchase Program
Amount of treasury stock acquired.
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Discount and rebate liability
Increase (decrease) in discount and rebate liabilities.
Secured promissory note
us-gaap_IncomeTaxReconciliationTaxCreditsResearch
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount