Document And Entity Information
?IPR&D - celiprolol
Note To Financial Statement Details Textual
Significant Accounting Policies
Note C - Inventories
Note D - Debt Obligations
Note G - Stock and Warrants
Note H - Stock-based Compensation
Note I - Fair Value of Financial Instruments
Note J - Net Loss Per Share
Liabilities, Noncurrent [Abstract]
Note K - Leases
Prepaid expenses
Note L - Merger
Other current assets
us-gaap_LongTermLineOfCredit
Line of credit payable
Note C - Inventories - Summary of Inventory (Details)
zvra_EmployeeStockPurchasePlanMaximumNumberOfIssuableShares
Employee Stock Purchase Plan, Maximum Number of Issuable Shares (in shares)
Maximum number of shares that may be issued under Employee Stock Purchase Plan.
Note D - Debt Obligations - Aggregate Principal Amount (Details)
Note D - Debt Obligations - Future Minimum Principal Payments (Details)
us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents
Cash
Note G - Stock and Warrants - Reserved Authorized Shares of Common Stock for Future Issuance (Details)
Inventory
Note G - Stock and Warrants - Common Stock Activity (Details)
us-gaap_LiabilitiesCurrent
Total current liabilities
Schedule of Maturities of Long-Term Debt [Table Text Block]
Note H - Stock-based Compensation - Stock-based Compensation Expense (Details)
Note I - Fair Value of Financial Instruments - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)
Note I - Fair Value of Financial Instruments - Fair Value Assumptions for Warrant Liabilities (Details)
Note I - Fair Value of Financial Instruments - Reconciliation of Beginning and Ending Balances for Derivative and Warrant Liability Measured at Fair Value on Recurring Basis (Details)
Other current liabilities
us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable
Business Combination, Consideration Transferred, Equity Interests Issued and Issuable
Note J - Net Loss Per Share - Anti-dilutive Securities (Details)
Note J - Net Loss Per Share - Earnings Per Share (Details)
us-gaap_BusinessCombinationConsiderationTransferred1
Business Combination, Consideration Transferred
Note K - Leases - Lease Cost (Details)
Note K - Leases - Supplement Cash Flow Information Related to Leases (Details)
Note K - Leases - Supplement Balance Sheet Information Related to Lease (Details)
Note K - Leases - Maturities of Lease Liabilities (Details)
us-gaap_BusinessCombinationConsiderationTransferredOther1
Business Combination, Consideration Transferred, Other
Note L - Merger - Estimates and Assumptions Related to Fair Value of Assets and Liabilities Acquired (Details)
Note L - Merger - Pro Forma Combined Results of Operations (Details)
Note L - Merger - Reconciliation of Contingent Consideration Liabilities (Details)
Notes To Financial Statements
Notes To Financial Statements [Abstract]
us-gaap_BusinessAcquisitionSharePrice
Business Acquisition, Share Price (in dollars per share)
Arimoclomol Purchase Agreement [Member]
Represents Arimoclomol Purchase Agreement.
US Treasury Securities [Member]
Foreign currency translation adjustment
zvra_AssetAcquisitionConsiderationTransferredEstimatedReserveLiability
Asset Acquisition, Consideration Transferred, Estimated Reserve Liability
Represents estimated reserve liability for asset acquisition consideration transferred.
zvra_ContractWithCustomerClawbackLiability
Contract with Customer, Clawback Liability
Represents clawback liability for contract with customer
Other comprehensive loss:
Pro forma net loss
Business Acquisition, Pro Forma Information [Table Text Block]
Pro forma revenue
us-gaap_PaymentsToAcquireNotesReceivable
Payments to Acquire Notes Receivable
Line of credit payable
zvra_SharesAndWarrantsIssuedPricePerShare
Shares and Warrants Issued, Price Per Share (in dollars per share)
The price per share of shares and warrants issued.
us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent
Accounts payable and accrued expenses
JMP and RBCCM [Member]
Represents JMP Securities LLC ("JMP") and RBC Capital Markets, LLC ("RBCCM").
Goodwill and Intangible Assets Disclosure [Text Block]
zvra_EquityDistributionAgreementMaximumAggregateOfferingPrice
Equity Distribution Agreement, Maximum Aggregate Offering Price
The maximum aggregate offering price under the equity distribution agreement.
zvra_EquityDistributionAgreementCommissionFeePercentageOfGrossSales
Equity Distribution Agreement, Commission Fee, Percentage of Gross Sales
The percentage of gross sales for commission fee under the equity distribution agreement.
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]
zvra_PaymentsOfPrincipalOnInsuranceFinancingArrangements
Payment of principal on insurance financing arrangements
Represents payments of principal on insurance financing arrangements.
us-gaap_PolicyTextBlockAbstract
Accounting Policies
us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Purchases of property and equipment
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized (in shares)
Supplemental disclosure of noncash financing activities:
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized (in shares)
Cost accrued in connection with the Credit Agreement (Note D)
Liabilities and stockholders' equity
us-gaap_LossContingencyAccrualAtCarryingValue
Loss Contingency Accrual
Liabilities, Current [Abstract]
Weighted average number of shares of common stock outstanding:
Operating lease liabilities
us-gaap_Assets
Total assets
Supplemental cash flow information:
Plan Name [Axis]
Plan Name [Domain]
us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic
Net loss
us-gaap_SubleaseIncome
Less: sublease income
Mergers, Acquisitions and Dispositions Disclosures [Text Block]
us-gaap_IncomeTaxReceivable
Income Taxes Receivable
Share-Based Payment Arrangement [Text Block]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
ATM Agreement Sales [Member]
Represents for At-the-Market Agreement Sales.
Schedule of Business Acquisitions by Acquisition, Contingent Consideration [Table Text Block]
Business Description and Basis of Presentation [Text Block]
Award Type [Domain]
Net Income (loss)
Net loss
Net Income (Loss) Attributable to Parent
Net loss
Award Type [Axis]
us-gaap_FiniteLivedIntangibleAssetsNet
Finite-Lived Intangible Assets, Net
Intangible assets, net
Performance Shares [Member]
Share-Based Payment Arrangement [Member]
Warrant [Member]
Inventory [Axis]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Inventory [Domain]
Antidilutive Securities [Axis]
Antidilutive Securities, Name [Domain]
us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill
Indefinite-Lived Intangible Assets (Excluding Goodwill)
Commitments and Contingencies Disclosure [Text Block]
us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
less: accumulated depreciation and amortization
Property and equipment, net
Goodwill acquired
Goodwill
Derivative Instrument [Axis]
Derivative Contract [Domain]
Cash flows from investing activities:
zvra_FinancingReceivableMaximumLimit
Financing Receivable, Maximum Limit
The maximum limit of the financing receivable.
Acer Therapeutics Inc [Member]
Represents Acer Therapeutics Inc.
Bridge Loan [Member]
Earnings Per Share [Text Block]
zvra_ClassOfWarrantsOrRightExercisedDuringPeriod
Class of Warrants or Right, Exercised During Period (in shares)
The number of warrants or rights exercised during period.
Arimoclomol EAP [Member]
Related to Arimoclomol EAP.
us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Accounts payable and accrued expenses
us-gaap_IncomeTaxExpenseBenefit
Income tax benefit
Consolidation, Variable Interest Entity, Policy [Policy Text Block]
SWK Loans [Member]
Represents the SWK Loans.
zvra_DebtInstrumentInterestRateStatedPercentageIfUnpaidWithinSixMonths
Debt Instrument, Interest Rate, Stated Percentage, If Unpaid Within Six Months
Contractual interest rate for funds borrowed, under the debt agreement, if unpaid within six months.
Nantahala Note [Member]
Represents the Nantahala Note.
zvra_DebtInstrumentInterestSharesConsecutiveTradingDaysForCalculationOfVWAP
Debt Instrument, Interest, Shares, Consecutive Trading Days For Calculation of VWAP (Day)
The consecutive trading days for calculation of VWAP for interest to be paid in shares on debt instrument.
zvra_DebtInstrumentInterestRateIncreaseInStatedPercentageIfUnpaidWithinSixMonths
Debt Instrument, Interest Rate, Increase in Stated Percentage, If Unpaid Within Six Months
Increase in the contractual interest rate for funds borrowed, under the debt agreement, if unpaid within six months.
zvra_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuableConversionRatio
Business Combination, Consideration Transferred, Equity Interests Issued and Issuable, Conversion Ratio
Conversion ratio of equity interests of the acquirer, including instruments or interests issued or issuable in consideration for the business combination.
zvra_VwapConsecutiveTradingDays
VWAP, Consecutive Trading Days (Year)
The consecutive trading days for VWAP.
Warrants [Policy Text Block]
Represents the policy for warrants.
Aquestive Therapeutics [Member]
Represents Aquestive Therapeutics (formerly known as MonoSol Rx, LLC).
zvra_AssetAcquisitionSharePrice
Asset Acquisition, Share Price (in dollars per share)
The share price of equity interest issued in asset acquisition.
Wells Fargo Bank, N.A. [Member]
Represents the "Wells Fargo Bank, N.A."
License Agreement and Termination Agreement [Member]
Represents License Agreement and Termination Agreement.
Marathon Convertible Notes [Member]
Represents the Marathon Convertible Notes.
zvra_MaximumRoyaltyObligation
Maximum Royalty Obligation
Amount of maximum royalty obligation.
Worldwide, Excluding Europe [Member]
Represents worldwide, excluding Europe.
SWK Loans and Marathon Notes [Member]
Represents the SWK Loans and Marathon Notes.
Cash and cash equivalents
Relief [Member]
Represents Relief.
zvra_MaximumRoyaltyPercentage
Maximum Royalty Percentage
Percentage of maximum royalty.
zvra_AddiitonalPaymentOnFirstAnniversary
Addiitonal Payment on First Anniversary
Amount of additional payment on first anniversary.
us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities
Other liabilities
zvra_UpfrontPayment
Upfront Payment
Amount of upfront payment.
Stock based compensation expense
Share-Based Payment Arrangement, Expense
zvra_LineOfCreditFacilityMaximumBorrowingCapacityPercentageOfInvestments
Line of Credit Facility, Maximum Borrowing Capacity, Percentage of Investments
Percentage of investments outstanding for maximum borrowing capacity of the debt instrument.
Amendment Flag
us-gaap_ComprehensiveIncomeNetOfTax
Comprehensive loss
City Area Code
Use of Estimates, Policy [Policy Text Block]
New Accounting Pronouncements, Policy [Policy Text Block]
us-gaap_DebtInstrumentPeriodicPaymentInterest
Debt Instrument, Periodic Payment, Interest
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding (in shares)
Balance (in shares)
Balance (in shares)
Preferred stock, shares outstanding (in shares)
Possible Future Issuances Under Employee Stock Purchase Plans [Member]
Represents possible future issuances under employee stock purchase plans.
Warrant liability
Derivative and Warrant Liability, Noncurrent
Noncurrent Carrying amount of derivative and warrant liability.
Current Fiscal Year End Date
us-gaap_DebtInstrumentBasisSpreadOnVariableRate1
Debt Instrument, Basis Spread on Variable Rate
us-gaap_DebtInstrumentInterestRateStatedPercentage
Debt Instrument, Interest Rate, Stated Percentage
Variable lease cost
us-gaap_LeaseCost
Total lease costs
us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Prepaid expenses and other assets
Operating leases
Document Fiscal Period Focus
Operating lease cost
Document Fiscal Year Focus
Short-term lease cost
Lease, Cost [Table Text Block]
us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability
Finance leases
Document Period End Date
us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
Operating leases
Operating leases (in years) (Year)
Entity File Number
Entity Emerging Growth Company
us-gaap_DebtInstrumentFaceAmount
Debt Instrument, Face Amount
Document Type
Entity Small Business
Entity Shell Company
Document Information [Line Items]
Document Information [Table]
us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue
Balance
Balance
Entity Filer Category
Debt Instrument [Axis]
Entity Current Reporting Status
Debt Instrument, Name [Domain]
Variable Rate [Domain]
Change in fair value measurement
Amount of cumulative effect adjustment for financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.
Prime Rate [Member]
zvra_FairValueAdjustmentOfPutOptionNetOfTax
Fair Value Adjustment of Put Option, Net of Tax
After tax amount of expense (income) related to adjustment to fair value of put option.
Schedule of Long-Term Debt Instruments [Table Text Block]
Variable Rate [Axis]
Stock-based compensation expense
us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables
Accounts and other receivables
Statement of Comprehensive Income [Abstract]
Entity Tax Identification Number
Entity Central Index Key
Entity Registrant Name
Entity [Domain]
Legal Entity [Axis]
Entity Address, Address Line One
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
us-gaap_AmortizationOfIntangibleAssets
Amortization of Intangible Assets
ecd_NonRule10b51ArrTrmntdFlag
Non-Rule 10b5-1 Arrangement Terminated [Flag]
us-gaap_TreasuryStockValueAcquiredCostMethod
Shares repurchased as part of the Share Repurchase Program
Entity Address, City or Town
ecd_Rule10b51ArrTrmntdFlag
Rule 10b5-1 Arrangement Terminated [Flag]
ecd_Rule10b51ArrAdoptedFlag
Rule 10b5-1 Arrangement Adopted [Flag]
Entity Address, Postal Zip Code
us-gaap_TreasuryStockCommonValue
Treasury Stock, Common, Value
Entity Address, State or Province
ecd_NonRule10b51ArrAdoptedFlag
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Material Terms of Trading Arrangement [Text Block]
us-gaap_TreasuryStockValue
Treasury stock, at cost
Entity Common Stock, Shares Outstanding
zvra_SaleOfStockAuthorizedAmount
Sale of Stock, Authorized Amount
Amount of stock authorized for sale.
us-gaap_IncreaseDecreaseInInventories
Inventories
Trading Symbol
us-gaap_StockIssuedDuringPeriodSharesAcquisitions
Stock Issued During Period, Shares, Acquisitions (in shares)
us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans
Stock Issued During Period, Shares, Employee Stock Purchase Plans (in shares)
Local Phone Number
us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity
Line of Credit Facility, Remaining Borrowing Capacity
Common stock issued as a result of stock options exercised (in shares)
us-gaap_TableTextBlock
Notes Tables
Issuance of common stock as part of the Employee Stock Purchase Plan
us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures (in shares)
Issuance of common stock for options exercised
Selling, general and administrative
Secured Overnight Financing Rate (SOFR) [Member]
Risk-free interest rate
Line of Credit Facility, Lender [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
us-gaap_StockIssuedDuringPeriodSharesNewIssues
Stock Issued During Period, Shares, New Issues (in shares)
Issuance of common stock in exchange for consulting services
us-gaap_StockIssuedDuringPeriodSharesIssuedForServices
Common stock issued as compensation to third parties (in shares)
Lender Name [Axis]
us-gaap_LiabilitiesAndStockholdersEquity
Total liabilities and stockholders' equity
us-gaap_StockIssuedDuringPeriodValueNewIssues
Stock Issued During Period, Value, New Issues
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Accumulated other comprehensive income (loss)
Research and development
Debt Disclosure [Text Block]
us-gaap_InterestExpense
Interest expense
Measurement Input, Price Volatility [Member]
Change in assets and liabilities:
Measurement Input, Risk Free Interest Rate [Member]
Schedule of Authorized Shares of Common Stock Reserved for Future Issuance [Table Text Block]
Tabular disclosure of authorized shares of common stock reserved for future issuance.
us-gaap_DisclosureTextBlockAbstract
Notes to Financial Statements
Inventory Disclosure [Text Block]
Subsequent Event [Member]
Measurement Input, Expected Dividend Rate [Member]
Operating lease liabilities, less current portion
Measurement Input, Expected Term [Member]
Possible Future Issuances Under Equity Incentive Plans [Member]
Represents possible future issuances under equity incentive plans.
Total operating lease liabilities
Lease liabilities, operating leases
Non-cash interest expense
Subsequent Event Type [Axis]
Current portion of operating lease liabilities
Subsequent Event Type [Domain]
us-gaap_FinanceLeaseLiabilityCurrent
Other current liabilities
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
us-gaap_FinanceLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList
us-gaap_FinanceLeaseLiabilityNoncurrent
Other long-term liabilities
Subsequent Events [Text Block]
Finance Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
us-gaap_FinanceLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList
Operating lease right-of-use assets
Total operating lease right-of-use assets
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue
Total lease payments, operating leases
zvra_SharebasedCompensationArrangementBySharebasedPaymentAwardNumberOfSharesReservedForIssuanceIncrementalPercentageOfCapitalStockOutstanding
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Reserved for Issuance, Incremental Percentage of Capital Stock Outstanding
Represents the share based compensation arrangement by share based payment award number of shares reserved for issuance incremental percentage of capital stock outstanding.
Financing cash flows from finance leases
Repayment of principal on finance lease liabilities
us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
Less: future interest expense, operating leases
us-gaap_FinanceLeaseLiability
Lease liabilities, finance leases
2014 Equity Incentive Plan [Member]
Represents the two thousand fourteen equity incentive plan.
zvra_IncreaseInCommonStockReservedForIssuance
Increase in Common Stock Reserved for Issuance (in shares)
Amount of increase in common stock reserved for issuance.
Measurement Input Type [Axis]
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree
2027, operating leases
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear
Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year
Measurement Input Type [Domain]
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour
2028, operating leases
us-gaap_UnrealizedGainLossOnInvestments
Unrealized Gain (Loss) on Investments
us-gaap_FinanceLeaseRightOfUseAsset
Property and equipment, net
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
us-gaap_FinanceLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList
Acer Warrants [Member]
Represents the Acer warrants.
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo
Finite-Lived Intangible Asset, Expected Amortization, Year Two
Net Investment in Lease, before Allowance for Credit Loss
zvra_CommonStockRegisteredShares
Common Stock Registered, Shares (in shares)
Shares registered as apart of an S-3 filing.
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree
Finite-Lived Intangible Asset, Expected Amortization, Year Three
zvra_GainLossOnContingentConsiderationChangeInFairValue
Gain (Loss) on Contingent Consideration, Change in Fair Value
Represents the gain/(loss) on contingent consideration from the changes in fair value over the period.
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour
Finite-Lived Intangible Asset, Expected Amortization, Year Four
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
2025, operating leases
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
2026, operating leases
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths
Finite-Lived Intangible Asset, Expected Amortization, Year One
us-gaap_FairValueAdjustmentOfWarrants
Fair value adjustment related to warrant and CVR liability
The Investor Warrant [Member]
Represents the warrant held by the investor.
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Relief Therapeutics [Member]
Relates to Relief Therapeutics.
Warrants to Purchase Common Stock [Member]
Represents warrants to purchase common stock.
Other long-term assets
us-gaap_ShareBasedCompensation
Stock-based compensation expense
us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear
2024 (excluding the three months ended March 31, 2024), operating leases
Deferred collaboration funding
Amount of liabilities incurred for deferred collaboration funding assumed on the acquisition date.
Accounts payable and accrued expenses
Amount of liability incurred for accounts payable and accrued expenses assumed at acquisition date.
us-gaap_FiniteLivedIntangibleAssetUsefulLife
Finite-Lived Intangible Asset, Useful Life (Year)
zvra_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseLiabilities
Operating lease liabilities
Amount of liabilities incurred for operating leases assumed at the acquisition date.
Approved product - OLPRUVA
Amount of the approved product, OLPRUVA, acquired at the acquisition date.
Operating expenses:
zvra_RoyaltyRevenuePercent
Royalty Revenue, Percent
Represents the royalty revenue expressed as a percentage.
Total assets
zvra_RevenueRecognitionMilestoneMethodAdditionalRevenueToBeRecognized
Revenue Recognition, Milestone Method, Additional Revenue to be Recognized
The amount of additional consideration to be recognized for the milestone or milestones.
Consulting Services [Member]
Information pertaining to consulting services.
Depreciation and amortization expense
CVR Liability [Member]
Represents the CVR liability.
Inventories
Total inventory
us-gaap_AssetsCurrent
Total current assets
zvra_FinanceLeaseCostTotal
Total finance lease cost
Represents total cost of fiance lease.
us-gaap_InvestmentsFairValueDisclosure
Investments, Fair Value Disclosure
Equity [Text Block]
zvra_LesseeLeaseRemainingTermOfContract
Lessee, Lease, Remaining Term of Contract (Year)
Remaining term of lessee's lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.
Lease Disclosure [Text Block]
The entire disclosure for operating, finance, sale leaseback leases.
Weighted average fair value (in dollars per share)
Represents the weighted average fair value under fair value assumptions for warrant liabilities.
us-gaap_TreasuryStockCommonShares
Treasury Stock, Common, Shares (in shares)
Change in fair value recognized in earnings
Share Repurchase Program [Member]
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Common stock, $0.0001 par value, 250,000,000 shares authorized, 43,426,186 shares issued and 41,850,494 shares outstanding as of March 31, 2024; 43,110,360 shares issued and 41,534,668 shares outstanding as of December 31, 2023
Measurement Frequency [Axis]
Adjustments to reconcile net loss to net cash used in operating activities:
Measurement Frequency [Domain]
Fair Value, Recurring [Member]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized (in shares)
Common stock, shares issued (in shares)
Common Stock, Shares, Issued (in shares)
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share (in dollars per share)
Schedule of Leases Cash Flow Information [Table Text Block]
Tabular disclosure of leases related to cash flow information.
Revenue from Contract with Customer [Policy Text Block]
Revision of Prior Period [Axis]
zvra_FinanceLeaseRightofuseAssetGross
Property and equipment, at cost
Gross amount of lessee's right to use underlying asset under finance lease.
Revision of Prior Period [Domain]
Previously Reported [Member]
Schedule of Leases Balance Sheet Information [Table Text Block]
Tabular disclosure of leases related to balance sheet.
Common shares reserved for future issuance (in shares)
Statistical Measurement [Domain]
Term Loans Under Credit Agreement [Member
Represents term loans under credit agreement.
Operating cash flows from operating leases
Accumulated Depreciation and Amortization [Member]
Primary financial statement caption encompassing accumulated depreciation and amortization.
Maximum [Member]
zvra_DebtInstrumentAvailableAmountUntilDecember312024
Debt Instrument, Available Amount Until December 31, 2024
Amount of debt available to be drawn until December 31, 2024.
Property and Equipment, At Cost [Member]
Primary financial statement caption encompassing property and plant at cost.
Minimum [Member]
zvra_DebtInstrumentNetProductSalesPerformanceBenchmark
Debt Instrument, Net Product Sales Performance Benchmark
Amount of performance benchmark of net product sales under debt instrument.
zvra_DebtInstrumentBasisSpreadOnVariableRateWhenPerformanceBenchmarkMeet
Debt Instrument, Basis Spread on Variable Rate When Performance Benchmark Meet
Percentage points added to the reference rate to compute the variable rate on the debt instrument when performance benchmark meet.
Product and Service [Axis]
Operating cash flows from short-term leases
zvra_DebtInstrumentAvailableAmountUntil18MonthsFollowingClosingDateMaximumEachDrawing
Debt Instrument, Available Amount Until 18 Months Following Closing Date, Maximum Each Drawing
Maximum each drawing for amount available under debt instrument to draw after 18 months of debt closing date.
Product and Service [Domain]
Fair value adjustment related to warrant and CVR liability
Amount of expense (income) related to adjustment to fair value of warrant liability and CVR Liability
Operating cash flows from variable lease costs
Statistical Measurement [Axis]
zvra_DebtInstrumentAvailableAmountUntil18MonthsFollowingClosingDate
Debt Instrument, Available Amount Until 18 Months Following Closing Date
Amount of debt available until 18 months following closing date under debt instrument.
Operating and Finance Lease, Liability, Maturity [Table Text Block]
Tabular disclosure of undiscounted cash flows of operating and finance lease liability. Includes, but is not limited to, reconciliation of undiscounted cash flows to operating and finance lease liability recognized in statement of financial position.
Undesignated preferred stock, $0.0001 par value, 10,000,000 shares authorized, no shares issued or outstanding as of March 31, 2024 or December 31, 2023
zvra_DebtInstrumentBasisSpreadOnVariableRateWhenPerformanceBenchmarkMeetInNextYear
Debt Instrument, Basis Spread on Variable Rate When Performance Benchmark Meet in Next Year
Percentage points added to the reference rate to compute the variable rate on the debt instrument when performance benchmark meet in next year.
Preferred stock, shares issued (in shares)
zvra_DebtInstrumentNetProductSalesPerformanceBenchmarkInNextYear
Debt Instrument, Net Product Sales Performance Benchmark in Next Year
Amount of performance benchmark of net product sales in next year under debt instrument.
zvra_DebtInstrumentMaximumInterestPaymentPercentage
Debt Instrument, Maximum Interest Payment, Percentage
Maximum amount of interest payment allowed under debt instrument as a percentage.
Cash paid for interest
zvra_DebtInstrumentFloorRate
Debt Instrument, Floor Rate
Floor rate of debt instrument.
Geographical [Axis]
Geographical [Domain]
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized (in shares)
Europe [Member]
zvra_LesseeLeaseOptionToTerminateTerm
Lessee, Lease, Option to Terminate, Term (Year)
Represents the terms of option to terminate lessee's lease.
OLPRUVA [Member]
Represents OLPRUVA.
us-gaap_InventoryNet
Inventory, Net
zvra_LesseeLeaseOptionToExtendMaximumTerm
Lessee, Lease, Option to Extend, Maximum Term (Year)
Represents maximum terms of option to extend lessee's lease.
Preferred stock, par value (in dollars per share)
Work in progress
Revenue, net
Revenue from Contract with Customer, Including Assessed Tax
Fair Value, Inputs, Level 3 [Member]
us-gaap_ForeignCurrencyTransactionGainLossBeforeTax
Loss (gain) on foreign currency exchange
Finished goods
Fair Value Hierarchy and NAV [Domain]
Fair Value, Inputs, Level 1 [Member]
Fair Value, Inputs, Level 2 [Member]
Fair Value Hierarchy and NAV [Axis]
Raw materials
Cash flows from operating activities:
Accounts and other receivables
Statement [Line Items]
us-gaap_AccountsReceivableNetCurrent
Accounts Receivable, after Allowance for Credit Loss, Current
Additional paid-in capital
AOCI Attributable to Parent [Member]
Stockholders’ equity:
Securities at fair value
us-gaap_NonoperatingIncomeExpense
Total other income (expense)
Other income (expense):
Fair Value Disclosures [Text Block]
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
Cash and cash equivalents, beginning of period
Cash and cash equivalents, end of period
Inventory, Policy [Policy Text Block]
Assets
License [Member]
Effect of exchange rate changes on cash and cash equivalents
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
Net decrease in cash and cash equivalents
us-gaap_Liabilities
Total liabilities
us-gaap_NetCashProvidedByUsedInFinancingActivities
Net cash provided by (used in) financing activities
Commitments and contingencies (Note D)
Sale of Stock [Axis]
Sale of Stock [Domain]
us-gaap_OperatingIncomeLoss
Loss from operations
us-gaap_ContractWithCustomerLiabilityRevenueRecognized
Contract with Customer, Liability, Revenue Recognized
us-gaap_NetCashProvidedByUsedInOperatingActivities
Net cash used in operating activities
Prepaid expenses and other current assets
us-gaap_NetCashProvidedByUsedInInvestingActivities
Net cash provided by (used in) investing activities
Counterparty Name [Axis]
Counterparty Name [Domain]
Total liabilities
Intangible asset amortization
Investment, Policy [Policy Text Block]
us-gaap_CostsAndExpenses
Total operating expenses
us-gaap_PaymentsForRepurchaseOfCommonStock
Payments to repurchase shares as part of the Share Repurchase Program
us-gaap_ProceedsFromWarrantExercises
Proceeds from Warrant Exercises
GPC Member
Information regarding the GPC License Agreement.
Retained Earnings [Member]
Undesignated Preferred Stock [Member]
Preferred stock that has been classified as undesignated.
Proceeds from issuance of stock
Treasury Stock, Common [Member]
Additional Paid-in Capital [Member]
Common Stock [Member]
Equity Components [Axis]
Equity Component [Domain]
Class of Warrant or Right [Axis]
Class of Warrant or Right [Domain]
Secured promissory note, net
us-gaap_NotesPayable
Secured promissory note, net
us-gaap_ClassOfWarrantOrRightOutstanding
Class of Warrant or Right, Outstanding (in shares)
us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
Loss before income taxes
us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)
us-gaap_LineOfCredit
Long-Term Line of Credit
us-gaap_DeferredFinanceCostsNet
Debt Issuance Costs, Net
Less: debt issuance costs
Plus: unamortized debt premium and debt issuance costs
us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
Revenue from Contract with Customer [Text Block]
us-gaap_DebtInstrumentUnamortizedDiscountPremiumNet
Unamortized original issue premium
Statement of Financial Position Location, Balance [Axis]
Statement of Financial Position Location, Balance [Domain]
Document Quarterly Report
Entity Incorporation, State or Country Code
Secured promissory note
us-gaap_DebtInstrumentCarryingAmount
Total minimum payments
General and Administrative Expense [Member]
Accounting Policies [Abstract]
Significant Accounting Policies [Text Block]
Document Transition Report
Entity Interactive Data Current
Security Exchange Name
Title of 12(b) Security
us-gaap_ProceedsFromIssuanceOfLongTermDebt
Proceeds from Issuance of Long-Term Debt
Receivable Type [Axis]
Receivable [Domain]
Research and Development Expense [Member]
Statement of Income Location, Balance [Axis]
Statement of Income Location, Balance [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
us-gaap_ContractualObligation
Contractual Obligation
us-gaap_RepaymentsOfNotesPayable
Repayments of Notes Payable
Antidilutive securities (in shares)
Asset Class [Axis]
Asset Class [Domain]
Statement [Table]
Statement of Financial Position [Abstract]
Basic and diluted (in shares)
Weighted average number of shares of common stock outstanding, basic and diluted (in shares)
Cost of product revenue (excluding $1,528 in intangible asset amortization for the three months ended March 31, 2024, shown separately below)
Business Acquisition [Axis]
Basic and diluted net loss per share of common stock (in dollars per share)
Net loss (in dollars per share)
Business Acquisition, Acquiree [Domain]
Basic and diluted net loss per share of common stock:
Statement of Cash Flows [Abstract]
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear
2024
us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High
Statement of Stockholders' Equity [Abstract]
Income Statement [Abstract]
Other comprehensive loss
Other comprehensive loss:
The 2023 Plan [Member]
Represents the 2023 Employment Inducement Award Plan.
us-gaap_BusinessCombinationContingentConsiderationLiability
Business Combination, Contingent Consideration, Liability
Balance
Balance
Proceeds from issuance of debt
Proceeds from Issuance of Debt
Pre-launch Inventory that Qualified for Capitalization [Member]
Represents pre-launch inventory that qualified for capitalization.
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths
2025
us-gaap_RepaymentsOfDebt
Repayment of debt
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo
2026
Interest on lease liabilities
us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares (in shares)
us-gaap_FinanceLeaseLiabilityPaymentsDue
Total lease payments, finance leases
Schedule of Inventory, Noncurrent [Table Text Block]
Amortization of right-of-use assets
us-gaap_FinanceLeaseLiabilityUndiscountedExcessAmount
Less: future interest expense, finance leases
us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths
2025, finance leases
us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo
2026, finance leases
us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree
2027, finance leases
us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour
2028, finance leases
Asset Acquisition [Axis]
srt_StockRepurchaseProgramAuthorizedAmount1
Stock Repurchase Program, Authorized Amount
us-gaap_AssetAcquisitionConsiderationTransferred
Asset Acquisition, Consideration Transferred
Interest and other income, net
Represents the amount of interest and other income (expense), net, recognized during the period.
Share Repurchase Program [Domain]
Share Repurchase Program [Axis]
us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear
2024 (excluding the three months ended March 31, 2024), finance leases
Liabilities, Noncurrent
Asset Acquisition, Contingent Consideration, Liability, Current
Finance leases (Year)
Cash flows from financing activities:
us-gaap_AssetAcquisitionConsiderationTransferredEquityInterestIssuedAndIssuable
Asset Acquisition, Consideration Transferred, Equity Interest Issued and Issuable
Schedule of Common Stock Outstanding Roll Forward [Table Text Block]
Warrants [Member]
Information pertaining to warrants.
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Other long-term liabilities
Asset Acquisition [Domain]
Consulting fees paid in common stock
The amount of consulting fees are paid in stock.
Fair value adjustment related to investments
Fair value adjustment related to investments
Amount of expense (income) related to adjustment to fair value of investments.
zvra_IncreaseDecreaseInOperatingLeaseRightofuseAsset
Operating lease right-of-use assets
The amount of increase (decrease) in operating lease right-of-use assets.
zvra_FinanceLeaseLiabilityToBePaidAfterYearFour
Thereafter, finance leases
Amount of lessee's undiscounted obligation for lease payment for finance lease to be paid after fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).
us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet
Fair Value of Net Assets Acquired
zvra_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour
Thereafter, operating leases
Amount of lessee's undiscounted obligation for lease payment for operating lease due after fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).
Current portion of discount and rebate liabilities
Current portion of discount and rebate liabilities.
Discount and rebate liabilities, less current portion
Noncurrent portion of discount and rebate liabilities.
us-gaap_StockholdersEquity
Total stockholders' equity
Balance
Balance
us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities
Class of Stock [Axis]
Class of Stock [Domain]
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets
us-gaap_PaymentsForProceedsFromInvestments
Maturities (purchases) of investments
Discount and rebate liability
Increase (decrease) in discount and rebate liabilities.
Secured promissory note
Property, plant, and equipment
Other noncurrent assets